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Molecular Basis of Inheritance

174 questions · Biology · NEET
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Molecular Basis of Inheritance

174 questions · Biology · NEET

  1. Match List-I with List-II Choose the correct answer from the options given below: Includes table2025 · Q14 · MCQ
  2. Which of the following are the post-transcriptional events in an eukaryotic cell? A. Transport of pre-mRNA to cytoplasm prior to splicing. B. Removal of introns and joining of exons. C. Addition of methyl group at 5' end of hnRNA. D.…2025 · Q17 · MCQ
  3. Given below are two statements: Statement I: In the RNA world, RNA is considered the first genetic material evolved to carry out essential life processes. RNA acts as a genetic material and also as a catalyst for some important biochemical…2025 · Q34 · MCQ
  4. Given below are two statements : Statement 1 : Transfer RNAs and ribosomal RNA do not interact with mRNA. Statement II : RNA interference (RNAi) takes place in all eukaryotic organisms as a method of cellular defence. In the light of the…2025 · Q35 · MCQ
  5. Who proposed that the genetic code for amino acids should be made up of three nucleotides?2025 · Q68 · MCQ
  6. Which factor is important for termination of transcription?2025 · Q72 · MCQ
  7. Which chromosome in the human genome has the highest number of genes?2025 · Q8 · MCQ
  8. The lactose present in the growth medium of bacteria is transported to the cell by the action of2024 · Q12 · MCQ
  9. A transcription unit in DNA is defined primarily by the three regions in DNA and these are with respect to upstream and down stream end;2024 · Q32 · MCQ
  10. Which of the following statement is correct regarding the process of replication in E.coli?2024 · Q39 · MCQ
  11. Match List I with List II Choose the correct answer from the options given below: Includes table2024 · Q48 · MCQ
  12. Match List I with List II : Choose the correct answer from the options given below : Includes table2024 · Q63 · MCQ
  13. Which one is the correct product of DNA dependent RNA polymerase to the given template? 3'TACATGGCAAATATCCATTCA5'2024 · Q69 · MCQ
  14. Match List I with List II: Choose the correct answer from the options given below : Includes table2024 · Q96 · MCQ
  15. Given below are two statements regarding RNA polymerase in prokaryotes. Statement I : In prokaryotes, RNA polymerase is capable of catalysing the process of elongation during transcription. Statement II : RNA polymerase associate…2024 · Q15 · MCQ
  16. Given below are two statements: Statement I: In eukaryotes there are three RNA polymerases in the nucleus in addition to the RNA polymerase found in the organelles. Statement II: All the three RNA polymerases in eukaryotic nucleus have…2024 · Q26 · MCQ
  17. In a chromosome, there is a specific DNA sequence, responsible for initiating replication. It is called as:2024 · Q3 · MCQ
  18. Given below are two statements : Statement I: In the lac operon, the z gene codes for beta-galactosidase which is primarily responsible for the hydrolysis of lactose into galactose and glucose. Statement II: In addition to lactose, glucose…2024 · Q36 · MCQ
  19. Given below are two statements : Statement I : RNA interference takes place in all Eukaryotic organisms as method of cellular defense. Statement II : RNAi involves the silencing of a specific mRNA due to a complementary single-stranded RNA…2024 · Q88 · MCQ
  20. The last chromosome sequenced in Human Genome Project was:2023 · Q16 · MCQ
  21. Name the component that binds to the operator region of an operon and prevents RNA polymerase from transcribing the operon.2023 · Q23 · MCQ
  22. Given below are two statements : Statement I : The process of copying genetic information from one strand of the DNA into RNA is termed as transcription. Statement II : A transcription unit in DNA is defined primarily by the three regions…2023 · Q38 · MCQ
  23. Which scientist conducted an experiment with 32P and 35S labelled phages for demonstrating that DNA is the genetic material?2023 · Q39 · MCQ
  24. Given below are two statements : Statement I : RNA being unstable, mutate at a faster rate. Statement II : RNA can directly code for synthesis of proteins hence can easily express the characters. In the light of the above statements,…2023 · Q50 · MCQ
  25. Select the correct statements about sickle cell anaemia. (A) There is a change in gene for beta globin. (B) In the beta globin, there is valine in the place of Lysine. (C) It is an example of point mutation. (D) In the normal gene U is…2023 · Q60 · MCQ
  26. Which one of the following acts as an inducer for lac operon ?2023 · Q68 · MCQ
  27. With reference to Hershey and Chase experiments. Select the correct statements. (A) Viruses grown in the presence of radioactive phosphorus contained radioactive DNA. (B) Viruses grown on radioactive sulphur contained radioactive proteins.…2023 · Q76 · MCQ
  28. The salient features of genetic code are : (A) The code is palindromic (B) UGA act as initiator codon (C) The code is unambiguous and specific (D) The code is nearly universal Choose the most appropriate answer from the options given below…2023 · Q78 · MCQ
  29. Unequivocal proof that DNA is the genetic material was first proposed by2023 · Q16 · MCQ
  30. What is the role of RNA polymerase III in the process of transcription in Eukaryotes?2023 · Q18 · MCQ
  31. Expressed Sequence Tags (ESTs) refers to2023 · Q24 · MCQ
  32. Upon exposure to UV radiation, DNA stained with ethidium bromide will show2023 · Q25 · MCQ
  33. Match List I with List II. Choose the correct answer from the options given below : Includes table2023 · Q57 · MCQ
  34. Given below are two statements: Statement I: In prokaryotes, the positively charged DNA is held with some negatively charged proteins in a region called nucleoid. Statement II: In eukaryotes, the negatively charged DNA is wrapped around…2023 · Q70 · MCQ
  35. Which one of the following is the sequence on corresponding coding strand, if the sequence on mRNA formed is as follows 5’AUCGAUCGAUCGAUCGAUCGAUCG AUCG 3’?2023 · Q80 · MCQ
  36. Given below are two statements Statement I : DNA polymerases catalyse polymerisation only in one direction, that is 5' → 3'. Statement II : During replication of DNA, on one strand the replication is continuous while on other strand it is…2022 · Q23 · MCQ
  37. Match List - I with List - II. Choose the correct answer from the options given below Includes table2022 · Q26 · MCQ
  38. Match List-I with List-II: Choose the correct answer from the options given below: Includes table2022 · Q35 · MCQ
  39. In lac operon, z gene codes for2022 · Q5 · MCQ
  40. Against the codon 5' UAC 3', what would be the sequence of anticodon on tRNA?2022 · Q83 · MCQ
  41. If A and C make 30% and 20% of DNA, respectively, what will be the percentage composition of T and G?2022 · Q92 · MCQ
  42. DNA polymorphism forms the basis of:2022 · Q15 · MCQ
  43. Read the following statements and choose the set of correct statements: (a) Euchromatin is loosely packed chromatin (b) Heterochromatin is transcriptionally active (c) Histone octamer is wrapped by negatively charged DNA in nucleosome (d)…2022 · Q21 · MCQ
  44. Transposons can be used during which one of the following?2022 · Q32 · MCQ
  45. If a geneticist uses the blind approach for sequencing the whole genome of an organism, followed by assignment of function to different segments, the methodology adopted by him is called as :2022 · Q42 · MCQ
  46. If the length of a DNA molecule is 1.1 metres, what will b the approximate number of base pairs?2022 · Q47 · MCQ
  47. In an E. Coli strain i gene gets mutated and its product can not bind the inducer molecule. If growth medium is provided with lactose, what will be the outcome?2022 · Q58 · MCQ
  48. The process of translation of mRNA to proteins begins as soon as:2022 · Q7 · MCQ
  49. Ten E.coli cells with 15N - dsDNA are incubated in medium containing 14N nucleotide. After 60 minutes, how many E.coli cells will have DNA totally free from 15N?2022 · Q80 · MCQ
  50. DNA strands on a gel stained with ethidium bromide when viewed under UV radiation, appear as2021 · Q10 · MCQ
  51. Complete the flow chart on central dogma. Includes diagram2021 · Q23 · MCQ
  52. What is the role of RNA polymerase III in the process of transcription in eukaryotes?2021 · Q38 · MCQ
  53. DNA fingerprinting involves identifying differences in some specific regions in DNA sequence, called as2021 · Q41 · MCQ
  54. Identify the correct statement.2021 · Q44 · MCQ
  55. If Adenine makes 30% of the DNA molecule, what will be the percentage of Thymine, Guanine and Cytosine in it?2021 · Q52 · MCQ
  56. Which of the following RNAs is not required for the synthesis of protein?2021 · Q71 · MCQ
  57. Which is the "Only enzyme" that has "Capability" to catalyse Initiation, Elongation and Termination in the process of transcription in prokaryotes?2021 · Q75 · MCQ
  58. Which one of the following statements about histones is wrong?2021 · Q87 · MCQ
  59. Statement I : The codon 'AUG' codes for methionine and phenylalanine. Statement II : 'AAA' and 'AAG' both codons code for the amino acid lysine. In the light of the above statements, choose the correct answer from the options given below.2021 · Q88 · MCQ
  60. If the distance between two consecutive base pairs is 0.34 nm and the total number of base pairs of a DNA double helix in a typical mammalian cell is 6.6 × 109 bp, then the length of the DNA is approximately2020 · Q48 · MCQ
  61. Which of the following statements is correct?2020 · Q49 · MCQ
  62. The first phase of translation is2020 · Q50 · MCQ
  63. Name the enzyme that facilitates opening of DNA helix during transcription.2020 · Q78 · MCQ
  64. Which of the following features of genetic code does allow bacteria to produce human insulin by recombinant DNA technology?2019 · Q10 · MCQ
  65. The shorter and longer arms of a submetacentric chromosome are referred to as:2019 · Q11 · MCQ
  66. Purines found both in DNA and RNA are:2019 · Q6 · MCQ
  67. Expressed Sequence Tags (ESTs) refers to :2019 · Q7 · MCQ
  68. Match the following genes of the Lac operon with their respective produces : Select the correct option. Includes table2019 · Q8 · MCQ
  69. Under which of the following conditions will there be no change in the reading frame of following mRNA? 5' AACAGCGGUGCUAUU 3'2019 · Q9 · MCQ
  70. Select the correct match :2018 · Q71 · MCQ
  71. The experimental proof for semi-conservative replication of DNA was first shown in a2018 · Q73 · MCQ
  72. Select the correct statement :2018 · Q74 · MCQ
  73. Select the correct match :2018 · Q75 · MCQ
  74. Many ribosomes may associate with a single mRNA to form multiple copies of a polypeptide simultaneously. Such strings of ribosomes are termed as2018 · Q76 · MCQ
  75. All of the following are part of an operon except2018 · Q77 · MCQ
  76. AGGTATCGCAT is a sequence from the coding strand of a gene. What will be the corresponding sequence of the transcribed mRNA?2018 · Q78 · MCQ
  77. During DNA replication, Okazaki fragments are used to elongate2017 · Q64 · MCQ
  78. If there are 999 bases in an RNA that codes for a protein with 333 amino acids, and the base at position 901 is deleted such that the length of the RNA becomes 998 bases, how many codons will be altered ?2017 · Q73 · MCQ
  79. The final proof for DNA as the genetic material came from the experiments of2017 · Q74 · MCQ
  80. Which of the following RNAs should be most abundant in animal cell ?2017 · Q76 · MCQ
  81. Spliceosomes are not found in cells of :2017 · Q77 · MCQ
  82. The association of histone H1 with a nucleosome indicates :2017 · Q78 · MCQ
  83. Which one of the following is the starter codon ?2016 · Q63 · MCQ
  84. Which of the following is required as inducer(s) for the expression of Lac operon?2016 · Q75 · MCQ
  85. A complex of ribosomes attached to a single strand of RNA is known as :2016 · Q76 · MCQ
  86. DNA-dependent RNA polymerase catalyzes transcription on one strand of the DNA which is called the2016 · Q60 · MCQ
  87. Taylor conducted the experiments to prove semiconservative mode of chromosome replication on2016 · Q67 · MCQ
  88. The equivalent of a structural gene is -2016 · Q68 · MCQ
  89. A molecule that can act as a genetic material must fulfill the traits given below, except2016 · Q69 · MCQ
  90. Which of the following rRNAs acts as structural RNA as well as ribozyme in bacteria ?2016 · Q70 · MCQ
  91. Identify the correct order of organisation of genetic material from largest to smallest :2015 · Q51 · MCQ
  92. Which one of the following is not applicable to RNA?2015 · Q60 · MCQ
  93. Balbiani rings are sites of :2015 · Q61 · MCQ
  94. Satellite DNA is important because it :2015 · Q62 · MCQ
  95. Gene regulation governing lactose operon of E.coli that involves the lac I gene product is2015 · Q60 · MCQ
  96. In sea urchin DNA, which is double stranded, 17% of the bases were shown to be cytosine, The percentages of the other three bases expected to be present in this DNA are2015 · Q61 · MCQ
  97. Transformation was discovered by :2014 · Q70 · MCQ
  98. Which one of the following is wrongly matched?2014 · Q71 · Multiple correct
  99. Select the correct option ;2014 · Q72 · MCQ
  100. The figure gives an important concept in the genetic implication of DNA . Fill the blanks A, B and C. Includes diagram2013 · Q19 · MCQ
  101. Satellite RNA are present in some :2013 · Q20 · MCQ
  102. Which of the following is not a property of the genetic code ?2013 · Q32 · MCQ
  103. Genes of interest can be selected from a genomic library by using :2013 · Q61 · MCQ
  104. One of the most frequently used techniques in DNA fingerprinting is :-2013 · Q62 · MCQ
  105. In an inducible operon, the genes are :2013 · Q63 · MCQ
  106. The diagram shows an important concept in the genetic implication of DNA. Fill in the blanks A to C. Includes diagram2013 · Q68 · MCQ
  107. Which enzyme will be produced in a cell in which there is a non-sense mutation in the lac Y gene ?2013 · Q69 · MCQ
  108. Which of the following statements is not true of two genes that show 50% recombination frequency ?2013 · Q70 · MCQ
  109. If one strand of DNA has the nitrogenous base sequence as ATCTG, what would be the complementary RNA stand sequence2012 · Q71 · MCQ
  110. Removal of introns and joining of exons in a defined order during transcription is called2012 · Q72 · MCQ
  111. Which one of the following is not a part of a transcription unit in DNA ?2012 · Q73 · MCQ
  112. Ribosomal RNA is actively synthesized in2012 · Q74 · MCQ
  113. Removal of RNA polymerase -III from nucleoplasm will affect the synthesis of2012 · Q75 · MCQ
  114. The unequivocal proof of DNA as the genetic material came from the studies on a :2011 · Q4 · MCQ
  115. What are those structures that appear as 'beads-on-string' in the chromosomes when viewed under electron microscope ?2011 · Q67 · MCQ
  116. Which one of the follwoing statements about the particular entity is true ?2010 · Q44 · MCQ
  117. In eukaryotic cell transcription, RNA splicing and RNA capping take place inside the -2010 · Q45 · MCQ
  118. The lac Operon consists of -2010 · Q46 · MCQ
  119. The 3'-5' phosphodiester linkages inside a polynucleotide chain serve to join -2010 · Q47 · MCQ
  120. Select the two correct statements out of the four (a-d) statements given below about lac operon. (a) Glucose or galactose may bind with the repressor and inactivate it (b) In the absence of lactose the repressor binds with the operator…2010 · Q69 · MCQ
  121. Which one of the following does not follow the central dogma of molecular biology ?2010 · Q79 · MCQ
  122. Which one of the following palindromic base sequences in DNA can be easily cut at about the middle by some particular restriction enzyme?2010 · Q80 · MCQ
  123. The one aspect which is not a salient feature of genetic code, is its being –2010 · Q81 · MCQ
  124. Semi-conservative replication of DNA was first demonstrated in :2009 · Q72 · MCQ
  125. Whose experiments cracked the DNA and discovered unequivocally that a genetic code is a "triplet" ?2009 · Q73 · MCQ
  126. Removal of introns and joining the exons in a defined order in a transcription unit is called :2009 · Q74 · MCQ
  127. What is not true for genetic code?2009 · Q75 · MCQ
  128. In the DNA molecule:2008 · Q70 · MCQ
  129. Which one of the following pairs of nitrogenous bases of nucleic acids, is wrongly matched with the category mentioned against it?2008 · Q71 · MCQ
  130. Which one of the following pairs of codons is correctly matched with their function or the signal for the particular amino acid ?2008 · Q72 · MCQ
  131. Polysome is formed by2008 · Q73 · MCQ
  132. One gene-one enzyme hypothesis was postulated by -2006 · Q61 · MCQ
  133. One turn of the helix in a B-form DNA is approximately -2006 · Q72 · MCQ
  134. Antiparallel strands of a DNA molecule means that-2006 · Q73 · MCQ
  135. Which antibiotic inhibits interaction between tRNA and mRNA during bacterial protein synthesis ?2006 · Q74 · MCQ
  136. Amino acid sequence, in protein synthesis is decided by the sequence of -2006 · Q75 · MCQ
  137. E. coli cells with a mustard z gene of the lac operon cannot grow in medium containing only lactose as the source of energy because -2005 · Q67 · MCQ
  138. Telomerase is an enzyme which is a -2005 · Q68 · MCQ
  139. Using imprints from a plate with complete medium and carrying bacterial colonies, you can select streptomycin resistant mutants and prove that such mutations do not originates as adaptation. These imprints need to be used -2005 · Q69 · MCQ
  140. Which one of the following hydrolyses internal phosphodiester bonds in a polynucleotide chain ?2005 · Q70 · MCQ
  141. Protein synthesis in an animal cell occurs -2005 · Q71 · MCQ
  142. Which one of the following makes use of RNA as a template to synthesize DNA -2005 · Q72 · MCQ
  143. During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at the point. What is the sequence called ?2005 · Q73 · MCQ
  144. In a mutational event, when adenine is replaced by guanine, it is a case of -2004 · Q57 · MCQ
  145. During transcription, if the nucleotide sequence of the DNA strand that is being coded is ATACG, then the nucleotide sequence in the mRNA would be -2004 · Q65 · MCQ
  146. Which form of RNA has a structure resembling clover leaf ?2004 · Q66 · MCQ
  147. After a mutation at a genetic locus the character of an organism changes due to the change in :-2004 · Q67 · MCQ
  148. The following ratio is generally constant for a given species :-2004 · Q68 · MCQ
  149. What does "lac" refer to in what we call the lac operon ?2003 · Q64 · MCQ
  150. During transcription, the DNA site at which RNA polymerase binds is called :-2003 · Q74 · MCQ
  151. In the genetic code dictionary, how many codons are used to code for all the 20 essential amino acids : -2003 · Q75 · MCQ
  152. During translation initiation in prokaryotes, a GTP molecule is needed in : -2003 · Q76 · MCQ
  153. What would happen if in a gene encoding a polypeptide of 50 amino acids, 25th codon (UAU) is mutated to UAA ?2003 · Q77 · MCQ
  154. Which one of the following triplet codes, is correctly matched with its specificity for an amino acid in protein synthesis or as 'start' or 'stop' codon ?2003 · Q78 · MCQ
  155. Degeneration of a genetic code is attributed to the : -2003 · Q79 · MCQ
  156. Which of the following reunites the exon segments after RNA splicing ?2002 · Q64 · MCQ
  157. In a DNA percentage of thymine is 20% then what is the percentage of guanine : -2002 · Q70 · MCQ
  158. Jacob and Monad studied lactose metabolism in E.Coli and proposed operon concept. Operon concept applicable for :2002 · Q71 · MCQ
  159. Transformation experiment was first performed on which bacteria : -2002 · Q72 · MCQ
  160. In E. Coli, during lactose metabolism repressor binds to : -2002 · Q73 · MCQ
  161. Exon part of m-RNAs have code for : -2002 · Q74 · MCQ
  162. Which of the following enzymes are used to join bits of DNA ?2002 · Q75 · MCQ
  163. Out of 64 codons, 61 codons code for 20 types of amino acid it is called : -2002 · Q76 · MCQ
  164. Change in sequence of nucleotide in DNA is called as -2002 · Q77 · MCQ
  165. Types of RNA polymerase required in nucleus for RNA synthesis : -2001 · Q57 · MCQ
  166. In Negative operon : -2001 · Q66 · MCQ
  167. m-RNA is synthesised on DNA template in which direction : -2001 · Q67 · MCQ
  168. Gene and cistron words are sometimes used synonymously because : -2001 · Q68 · MCQ
  169. Which of the following is initiation codon ?2000 · Q71 · MCQ
  170. Method of DNA replication in which two strands of DNA separates and synthesize new strands2000 · Q72 · MCQ
  171. Anticodon occurs in :2000 · Q73 · MCQ
  172. Length of one loop of B- DNA :2000 · Q74 · MCQ
  173. In three dimensional view the molecule of t-RNA is :2000 · Q75 · MCQ
  174. Similarity in DNA and RNA :2000 · Q76 · MCQ