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Molecular Basis of Inheritance question

2024 · Q69
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Molecular Basis of Inheritance question

2024 · Q69

NEETBiologyMolecular Basis of InheritanceMCQ+4 / −1

Which one is the correct product of DNA dependent RNA polymerase to the given template?

3'TACATGGCAAATATCCATTCA5'

  1. A
    5'AUGUACCGUUUAUAGGUAAGU3'
  2. B
    5'AUGUAAAGUUUAUAGGUAAGU3'
  3. C
    5'AUGUACCGUUUAUAGGGAAGU3'
  4. D
    5'ATGTACCGTTTATAGGTAAGT3'
View written solutionFree

Correct answer: A

DNA-dependent RNA polymerase is an enzyme responsible for transcribing DNA into RNA. During transcription, the RNA polymerase reads the template strand of DNA and synthesizes a complementary RNA strand. A key point in this process is that RNA polymerase builds RNA by replacing thymine (T) with uracil (U).

The provided DNA template is:

3'TACATGGCAAATATCCATTCA5'

To find the correct RNA sequence, we need to identify the complementary base for each base in the template strand while considering RNA bases. Remember, in RNA:

  • A (Adenine) pairs with U (Uracil)
  • T (Thymine) pairs with A (Adenine)
  • C (Cytosine) pairs with G (Guanine)
  • G (Guanine) pairs with C (Cytosine)

The complementary RNA sequence to the DNA template is generated as follows:

  • 3'T --> 5'A
  • 3'A --> 5'U
  • 3'C --> 5'G
  • 3'G --> 5'C
  • 3'T --> 5'A
  • 3'A --> 5'U
  • 3'T --> 5'A
  • 3'G --> 5'C
  • 3'G --> 5'C
  • 3'C --> 5'G
  • 3'A --> 5'U
  • 3'A --> 5'U
  • 3'T --> 5'A
  • 3'A --> 5'U
  • 3'T --> 5'A
  • 3'C --> 5'G
  • 3'C --> 5'G
  • 3'A --> 5'U
  • 3'T --> 5'A
  • 3'T --> 5'A
  • 3'C --> 5'G'

This constructs the RNA sequence:

5'AUGUACCGUUUAUAGGUAAGU3'

Thus, Option A correctly represents the RNA sequence transcribed by DNA-dependent RNA polymerase from the given DNA template:

Option A: 5'AUGUACCGUUUAUAGGUAAGU3'

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