- Anegative and inducible because repressor protein prevents transcription.
- Bpositive and inducible because it can be induced by lactose
- Cnegative and repressible because repressor protein prevents transcription
- Dfeedback inhibition because excess of -galactosidase can switch off transcription
View written solutionFree
Correct answer: A
The control of expression of lac operon is
negative (as it is turned off normally) and inducible.
Inducible operon is an operon which remains switched
off normally but becomes operational in the presence
of an inducer (lactose, actually allolactose a
metabolite of lactose, in case of lac operon). The
inducible operon generally functions in catabolic
pathways. In the presence of an inducer, the repressor
has a higher affinity for the inducer than for the operator
gene.
When lactose is added, a few lactose molecules
are carried into the cell by the enzyme lactose permease
as small amount of this enzyme is present in the cell
even when the operon is not working. These few lactose
molecules are converted into allolactose molecules
which act as an inducer and bind to the repressor (a
product of regulator gene). The repressor-inducer
complex fails to join with the operator gene, thus it is
turned on.
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