NEETBiologyMolecular Basis of InheritanceMCQ+4 / −1
The association of histone H1 with a nucleosome indicates :
- ADNA replication is occurring
- BTranscription is occurring
- CThe DNA is condensed into a Chromatin Fibre
- DThe DNA double helix is exposed
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Correct answer: C
Histones help in packaging of DNA. In eukaryotes, DNA packaging is carried out with the help of positively charged basic proteins called histones. Histones are of five types – H1 , H2A, H2B, H3 and H4 . H1 is attached over the linker DNA. Histone contains a large proportion of the positively charged (basic) amino acids, lysine and arginine in their structure. DNA is negatively charged due to the phosphate groups on its backbone. The result of these opposite charges is strong attraction and therefore, high binding affinity between histones and DNA.
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