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Molecular Basis of Inheritance question

2013 · Q69
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Molecular Basis of Inheritance question

2013 · Q69

NEETBiologyMolecular Basis of InheritanceMCQ+4 / −1
Which enzyme will be produced in a cell in which there is a non-sense mutation in the lac Y gene ?
  1. A
    Transacetylase
  2. B
    Lactose permease and transacetylase
  3. C
    Lactose permease
  4. D
    β\betaβ-galactosidase
View written solutionFree

Correct answer: D

A nonsense mutation is the one which stops polypeptide synthesis due to the formation of termination or non-sense codon. In lac operon, sequence of structural genes is Z, Y and A, which respectively code for β\beta β-galactosidase, lactose permease and transacetylase. If the gene Y has nonsense mutation, gene expression will stop at it, resulting in non-expression of both gene Y and successive gene A. Thus, only β\beta β-galactosidase enzyme will be produced.

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