NEETBiologyMolecular Basis of InheritanceMCQ+4 / −1
Which enzyme will be produced in a cell in which there is a non-sense mutation in the lac Y gene ?
- ATransacetylase
- BLactose permease and transacetylase
- CLactose permease
- D-galactosidase
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Correct answer: D
A nonsense mutation is the one which stops polypeptide synthesis due to the formation of termination or non-sense codon. In lac operon, sequence of structural genes is Z, Y and A, which respectively code for -galactosidase, lactose permease and transacetylase. If the gene Y has nonsense mutation, gene expression will stop at it, resulting in non-expression of both gene Y and successive gene A. Thus, only -galactosidase enzyme will be produced.
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