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Biomolecules question

2023 · 29 Jan · Shift 1 · Q6
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Biomolecules question

2023 · 29 Jan · Shift 1 · Q6

JEE MainChemistryBiomoleculesMCQ+4 / −1
Number of cyclic tripeptides formed with 2 amino acids A and B is :
  1. A
    2
  2. B
    3
  3. C
    5
  4. D
    4
View written solutionFree

Correct answer: D

  1. Understand the problem

We need the number of cyclic tripeptides that can be formed using two amino acids, AAA and BBB.

A tripeptide has 3 amino acid units. Since it is cyclic, arrangements related by rotation are considered the same.

So we must count distinct 3-membered cyclic sequences made from AAA and BBB.


  1. List all possible 3-letter sequences before cyclic equivalence

Using AAA and BBB, the possible sequences of length 3 are:

AAA, AAB, ABA, ABB, BAA, BAB, BBA, BBBAAA,\ AAB,\ ABA,\ ABB,\ BAA,\ BAB,\ BBA,\ BBBAAA, AAB, ABA, ABB, BAA, BAB, BBA, BBB

Total linear sequences =23=8=2^3=8=23=8.


  1. Identify sequences equivalent under cyclic rotation

For cyclic peptides, sequences differing only by rotation are identical.

(i) All same residues

  • AAAAAAAAA gives one cyclic peptide.
  • BBBBBBBBB gives one cyclic peptide.

So far: 222 distinct cyclic peptides.

(ii) Two AAA and one BBB

The linear forms are:

AAB, ABA, BAAAAB,\ ABA,\ BAAAAB, ABA, BAA

These are all cyclic rotations of one another:

AAB→ABA→BAAAAB \to ABA \to BAAAAB→ABA→BAA

Hence they represent one cyclic tripeptide.

(iii) Two BBB and one AAA

The linear forms are:

ABB, BAB, BBAABB,\ BAB,\ BBAABB, BAB, BBA

These are also cyclic rotations of one another:

ABB→BAB→BBAABB \to BAB \to BBAABB→BAB→BBA

Hence they represent one cyclic tripeptide.


  1. Total number of distinct cyclic tripeptides

Thus the distinct cyclic tripeptides are:

AAA, BBB, AAB(≡ABA≡BAA), ABB(≡BAB≡BBA)AAA,\ BBB,\ AAB(\equiv ABA \equiv BAA),\ ABB(\equiv BAB \equiv BBA)AAA, BBB, AAB(≡ABA≡BAA), ABB(≡BAB≡BBA)

Therefore, total number is

444
  1. Check options
  • A: 222 ❌
  • B: 333 ❌
  • C: 555 ❌
  • D: 444 ✅

  1. Comparison with stored answer

Stored correct answer: D

Our derived answer: D

They agree.

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