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Biomolecules question

2020 · 6 Sep · Shift 2 · Q17
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Biomolecules question

2020 · 6 Sep · Shift 2 · Q17

JEE MainChemistryBiomoleculesMCQ+4 / −1
Which one of the following statements is not true?
  1. A
    Lactose contains α\alphaα-glycosidic linkage between C1 of galactose and C4 of glucose
  2. B
    Lactose is a reducing sugar and it gives Fehling’s test
  3. C
    On acid hydrolysis, lactose gives one molecule of D(+)-glucose and one molecule of D(+)-galactose
  4. D
    Lactose (C11H22O11C_{11}H_{22}O_{11}C11​H22​O11​) is a disaccharide and it contains 8 hydroxyl groups
View written solutionFree

Correct answer: A

  1. Recall the structure of lactose

    Lactose is a disaccharide made of: D-galactose+D-glucose\text{D-galactose} + \text{D-glucose}D-galactose+D-glucose

    The glycosidic linkage in lactose is: β(1→4)\beta(1\to 4)β(1→4) That means the bond is formed between:

    • C1C_1C1​ of galactose
    • C4C_4C4​ of glucose
  2. Check each option

    Option A: Lactose contains α\alphaα-glycosidic linkage between C1C_1C1​ of galactose and C4C_4C4​ of glucose.

    • This is incorrect because lactose has a β(1→4)\beta(1\to 4)β(1→4) glycosidic linkage, not an α\alphaα-linkage.
    • So A is not true.

    Option B: Lactose is a reducing sugar and it gives Fehling’s test.

    • In lactose, one anomeric carbon remains free.
    • Therefore, lactose is a reducing sugar.
    • Reducing sugars give Fehling’s test.
    • So B is true.

    Option C: On acid hydrolysis, lactose gives one molecule of D(+)-glucose and one molecule of D(+)-galactose.

    • This is correct.
    • Hydrolysis of lactose yields: Lactose→acidhydrolysisD(+)-glucose+D(+)-galactose\text{Lactose} \xrightarrow[\text{acid}]{\text{hydrolysis}} \text{D(+)-glucose} + \text{D(+)-galactose}Lactosehydrolysisacid​D(+)-glucose+D(+)-galactose
    • So C is true.

    Option D: Lactose (C11H22O11C_{11}H_{22}O_{11}C11​H22​O11​) is a disaccharide and it contains 8 hydroxyl groups.

    • Lactose is indeed a disaccharide, but its correct molecular formula is: C12H22O11C_{12}H_{22}O_{11}C12​H22​O11​
    • Counting hydroxyl groups in lactose gives 888 hydroxyl groups.
    • In standard exam context, the intended fact is that lactose is a disaccharide with 888 hydroxyl groups.
    • Hence this statement is generally treated as true except for the apparent typo in the formula.
  3. Conclusion

    The clearly incorrect statement is: A\boxed{A}A​

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