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Coordination Compounds question

2019 · 8 Apr · Shift 2 · Q17
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Coordination Compounds question

2019 · 8 Apr · Shift 2 · Q17

JEE MainChemistryCoordination CompoundsMCQ+4 / −1
The compound that inhibits the growth of tumors is :
  1. A
    cis-[Pd(Cl)2(NH3)2][Pd(Cl)_2(NH_3)_2][Pd(Cl)2​(NH3​)2​]
  2. B
    trans-[Pd(Cl)2(NH3)2][Pd(Cl)_2(NH_3)_2][Pd(Cl)2​(NH3​)2​]
  3. C
    cis-[Pt(Cl)2(NH3)2][Pt(Cl)_2(NH_3)_2][Pt(Cl)2​(NH3​)2​]
  4. D
    transtranstrans-[Pt(Cl)2(NH3)2][Pt(Cl)_2(NH_3)_2][Pt(Cl)2​(NH3​)2​]
View written solutionFree

Correct answer: C

  1. The question asks for the coordination compound known to inhibit the growth of tumors.

  2. A very important anticancer drug in coordination chemistry is cisplatin.

  3. The formula of cisplatin is: cis-[PtCl2(NH3)2]\text{cis-}[PtCl_2(NH_3)_2]cis-[PtCl2​(NH3​)2​]

  4. Its cis geometry is essential for biological activity. The trans isomer, called transplatin, trans-[PtCl2(NH3)2]\text{trans-}[PtCl_2(NH_3)_2]trans-[PtCl2​(NH3​)2​] is not effective as an anticancer drug.

  5. Also, the commonly known tumor-inhibiting compound is the platinum complex, not the palladium analogue.

  6. Now evaluate the options:

    • A: cis-[PdCl2(NH3)2]\text{cis-}[PdCl_2(NH_3)_2]cis-[PdCl2​(NH3​)2​] — not the standard anticancer drug.
    • B: trans-[PdCl2(NH3)2]\text{trans-}[PdCl_2(NH_3)_2]trans-[PdCl2​(NH3​)2​] — incorrect.
    • C: cis-[PtCl2(NH3)2]\text{cis-}[PtCl_2(NH_3)_2]cis-[PtCl2​(NH3​)2​] — this is cisplatin, the antitumor compound.
    • D: trans-[PtCl2(NH3)2]\text{trans-}[PtCl_2(NH_3)_2]trans-[PtCl2​(NH3​)2​] — transplatin, not used for tumor inhibition.
  7. Therefore, the correct answer is: C: cis-[PtCl2(NH3)2]\boxed{\text{C: cis-}[PtCl_2(NH_3)_2]}C: cis-[PtCl2​(NH3​)2​]​

  8. Comparison with stored correct answer:

    • Stored correct answer: C
    • Derived answer: C
    • They match.
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