Statements related to human Insulin are given below.
Which statements is/are correct about genetically engineered Insulin?
(a) Pro-hormone insulin contain extra stretch of C-peptide
(b) A-peptide and B-peptide chains of insulin were produced separately in E.coli, extracted and combined by creating disulphide bond between them.
(c) Insulin used for treating Diabetes was extracted from Cattles and Pigs.
(d) Pro-hormone Insulin needs to be processed for converting into a mature and functional hormone.
(e) Some patients develop allergic reactions to the foreign insulin.
Choose the most appropriate answer from the options given below :
- A(a), (b) and (d) only
- B(b) only
- C(c) and (d) only
- D(c), (d) and (e) only
View written solutionFree
Correct answer: B
Option (b) is the correct answer as genetically engineered insulin has A-peptide and B-peptide chains of insulin which are produced separately in E.coli, then they are extracted and combined by creating disulphide bond between them.
Statement (a) is incorrect as genetically engineered insulin does not have an extra stretch of C-peptide. Statement (c) is incorrect as insulin obtained from cattles and pigs is not genetically engineered insulin. Statement (d) is incorrect because conversion of pro-insulin to insulin is not required during production of insulin by genetic engineering as A-peptide and B-peptide chains are produced separately. Statement (e) is incorrect as allergic reactions to insulin are mostly seen when the insulin is obtained from animals.
More from Biotechnology and Its Applications
- When gene targetting involving gene amplification is attempted in an individual's tissue to treat disease, it is known as :2021 · MCQ
- With regard to insulin choose correct options. (1) C-peptide is not present in mature insulin. (2) The insulin produced by rDNA technology has C-peptide. (3) The pro-insulin has C-peptide (4) A-peptide and B-peptide of insulin are…2021 · MCQ
- Which of the following statements is not correct?2020 · MCQ
- Match the following columns and select the correct option. Includes table2020 · MCQ
- Which of the following glucose transporters is insulin-dependent?2019 · MCQ
- In India, the organisation responsible for assessing the safety of introducing genetically modified organisms for public use is2018 · MCQ
- Which of the following is commonly used as a vector for introducing a DNA fragment in human lymphocytes?2018 · MCQ
- Use of bioresources by multinational companies and organisations without authorisation from the concerned country and its people is called2018 · MCQ