NEETBiologyBiotechnology and Its ApplicationsMCQ+4 / −1
In gene therapy of Adenosine Deaminase (ADA) deficiency, the patient requires periodic infusion of genetically engineered lymphocytes because:
- ARetroviral vector is introduced into these lymphocytes.
- BGene isolated from marrow cells producing ADA is introduced into cells at embryonic stages
- CLymphocytes from patient's blood are grown in culture, outside the body
- DGenetically engineered lymphocytes are not immortal cells.
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Correct answer: D
Option (d) is the correct answer as genetically engineered lymphocytes are not immortal cells and die after some time.
Option (c) is not the correct answer as the lymphocytes from patient's blood are grown in culture, outside the body but it is not the correct reason.
In option (b), if the gene isolated from bone marrow cells producing ADA is introduced into cells at early embryonic stages, it could be a permanent cure.
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