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Biomolecules question

2021 · 27 Aug · Shift 1 · Q9
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Biomolecules question

2021 · 27 Aug · Shift 1 · Q9

JEE MainChemistryBiomoleculesMCQ+4 / −1
Out of following isomeric forms of uracil, which one is present in RNA?
  1. A
    JEE Main 2021 (Online) 27th August Morning Shift Chemistry - Biomolecules Question 95 English Option 1
  2. B
    JEE Main 2021 (Online) 27th August Morning Shift Chemistry - Biomolecules Question 95 English Option 2
  3. C
    JEE Main 2021 (Online) 27th August Morning Shift Chemistry - Biomolecules Question 95 English Option 3
  4. D
    JEE Main 2021 (Online) 27th August Morning Shift Chemistry - Biomolecules Question 95 English Option 4
View written solutionFree

Correct answer: D

  1. Identify what is being asked

    The question asks: among the isomeric forms (tautomers) of uracil, which form is present in RNA?

  2. Recall the important concept

    Uracil is a pyrimidine base present in RNA. Like many carbonyl-containing nitrogen heterocycles, it can exist in tautomeric forms:

    • Lactam (keto) form
    • Lactim (enol) form

    In nucleic acids, the biologically relevant and predominant form is the lactam (diketo) form.

  3. Structure of uracil in RNA

    Uracil in RNA is specifically: 2,4-dioxo pyrimidine2,4\text{-dioxo pyrimidine}2,4-dioxo pyrimidine i.e. it contains two carbonyl groups at positions 2 and 4.

    So the correct isomeric form must be the one showing:

    • carbonyl group at C2C_2C2​
    • carbonyl group at C4C_4C4​
    • hydrogens on the two ring nitrogens as appropriate for the standard keto form
  4. Choose the matching option

    Since the standard form of uracil in RNA is the diketo (lactam) form, the correct option is the one corresponding to that structure.

    From the stored answer, this is Option D.

  5. Conclusion

    The form of uracil present in RNA is the diketo (lactam) form.

    Therefore, the correct answer is: D\boxed{D}D​

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