During replication of a bacterial chromosome DNA synthesis starts from a replication origin site and moves in a bidirectional way. This means that two replication forks move away from the origin site in opposite directions, leading to the synthesis of two new DNA strands simultaneously. RNA primers are involved in the initiation of DNA synthesis, but they are eventually replaced by DNA nucleotides during the process. Telomerase is not involved in bacterial DNA replication as bacteria have circular chromosomes and do not have the telomere sequences found in eukaryotic chromosomes.