JEE MainChemistryBiomoleculesMCQ+4 / −1
Two nucleotides are joined together by a linkage known as :
- APhosphodiester linkage
- BGlycosidic linkage
- CDisulphide linkage
- DPeptide linkage
View written solutionFree
Correct answer: A
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Identify what joins nucleotides in nucleic acids
A nucleotide consists of:
- a nitrogenous base,
- a pentose sugar,
- a phosphate group.
In DNA and RNA, nucleotides are connected to each other through the phosphate group linking the sugars of adjacent nucleotides.
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Name of this linkage
The bond formed between the phosphate group of one nucleotide and the sugar of another nucleotide is called a phosphodiester linkage.
Specifically, it forms the sugar-phosphate backbone of nucleic acids.
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Check the other options
- A: Phosphodiester linkage — Correct. It joins two nucleotides in DNA/RNA.
- B: Glycosidic linkage — This links a sugar to a nitrogenous base, not two nucleotides together.
- C: Disulphide linkage — Found between sulfur-containing amino acids in proteins.
- D: Peptide linkage — Joins amino acids in proteins.
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Conclusion
Therefore, two nucleotides are joined by a phosphodiester linkage.
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