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Biomolecules question

2024 · 27 Jan · Shift 1 · Q1
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Biomolecules question

2024 · 27 Jan · Shift 1 · Q1

JEE MainChemistryBiomoleculesMCQ+4 / −1
Two nucleotides are joined together by a linkage known as :
  1. A
    Phosphodiester linkage
  2. B
    Glycosidic linkage
  3. C
    Disulphide linkage
  4. D
    Peptide linkage
View written solutionFree

Correct answer: A

  1. Identify what joins nucleotides in nucleic acids

    A nucleotide consists of:

    • a nitrogenous base,
    • a pentose sugar,
    • a phosphate group.

    In DNA and RNA, nucleotides are connected to each other through the phosphate group linking the sugars of adjacent nucleotides.

  2. Name of this linkage

    The bond formed between the phosphate group of one nucleotide and the sugar of another nucleotide is called a phosphodiester linkage.

    Specifically, it forms the sugar-phosphate backbone of nucleic acids.

  3. Check the other options

    • A: Phosphodiester linkage — Correct. It joins two nucleotides in DNA/RNA.
    • B: Glycosidic linkage — This links a sugar to a nitrogenous base, not two nucleotides together.
    • C: Disulphide linkage — Found between sulfur-containing amino acids in proteins.
    • D: Peptide linkage — Joins amino acids in proteins.
  4. Conclusion

    Therefore, two nucleotides are joined by a phosphodiester linkage.

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