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Biomolecules question

2024 · 4 Apr · Shift 1 · Q9
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Biomolecules question

2024 · 4 Apr · Shift 1 · Q9

JEE MainChemistryBiomoleculesMCQ+4 / −1
Which of the following is the correct structure of L-Glucose?
  1. A
    JEE Main 2024 (Online) 4th April Morning Shift Chemistry - Biomolecules Question 28 English Option 1
  2. B
    JEE Main 2024 (Online) 4th April Morning Shift Chemistry - Biomolecules Question 28 English Option 2
  3. C
    JEE Main 2024 (Online) 4th April Morning Shift Chemistry - Biomolecules Question 28 English Option 3
  4. D
    JEE Main 2024 (Online) 4th April Morning Shift Chemistry - Biomolecules Question 28 English Option 4
View written solutionFree

Correct answer: D

  1. Key idea: D/L notation for sugars

    For monosaccharides, the symbols D and L are assigned by comparing the configuration of the chiral carbon farthest from the carbonyl group with that of glyceraldehyde.

    • In an aldohexose like glucose, this is C-5.
    • If the −OH-OH−OH on C−5C-5C−5 is on the right in Fischer projection, it is D.
    • If the −OH-OH−OH on C−5C-5C−5 is on the left, it is L.
  2. Recall the Fischer projection of D-glucose

    The −OH-OH−OH arrangement from C−2C-2C−2 to C−5C-5C−5 in D-glucose is:

    Right, Left, Right, Right\text{Right, Left, Right, Right}Right, Left, Right, Right

  3. Obtain L-glucose from D-glucose

    L-glucose is the enantiomer of D-glucose, so every chiral center is inverted.

    Therefore, for L-glucose, the −OH-OH−OH positions from C−2C-2C−2 to C−5C-5C−5 become:

    Left, Right, Left, Left\text{Left, Right, Left, Left}Left, Right, Left, Left

  4. How to identify the correct option

    So the correct Fischer projection of L-glucose must have:

    • aldehyde group (CHOCHOCHO) at the top,
    • CH2OHCH_2OHCH2​OH at the bottom,
    • and −OH-OH−OH pattern from C−2C-2C−2 to C−5C-5C−5 as:

    L,R,L,LL, R, L, LL,R,L,L

  5. Comparison with the stored answer

    The stored correct answer is D. This matches the structure expected for L-glucose.

    Hence, the correct option is D.

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