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Coordination Compounds question

2014 · Q79
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Coordination Compounds question

2014 · Q79

NEETChemistryCoordination CompoundsMCQ+4 / −1
Which of the following complexes is used to be as an anticancer agent?
  1. A
    mer-[Co(NH3)3Cl3]
  2. B
    cis-PtCl2(NH3)2]
  3. C
    cis-K2[PtCl2Br2
  4. D
    Na2CoCl4
View written solutionFree

Correct answer: B

Among the options listed, Option B, cis-PtCl2(NH3)2], is the one used as an anticancer agent. This compound is commonly known as Cisplatin. It's a platinum-based drug used in chemotherapy and is effective in treating various types of cancers, including testicular, ovarian, and bladder cancer.

The effectiveness of Cisplatin in cancer treatment lies in its ability to form platinum-DNA adducts, which interfere with DNA repair mechanisms, leading to cell apoptosis (programmed cell death) in rapidly dividing cells, such as cancer cells.

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