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Principles of Inheritance and Variation question

2005 · Q20
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Principles of Inheritance and Variation question

2005 · Q20

NEETBiologyPrinciples of Inheritance and VariationMCQ+4 / −1
G-6-P dehydrogenase deficiency is associated with haemolysis of -
  1. A
    RBCs
  2. B
    Lymphocytes
  3. C
    Platelets
  4. D
    Leucocytes
View written solutionFree

Correct answer: A

Glucose-6-P dehydrogenase is the first enzyme of glucose oxidation during Pentose Phosphate Pathway. RBC contain haemoglobin which combines with oxygen to form oxyhaemoglobin which gives its oxygen for oxidation of food. In haemolysis there is destruction of RBCs with release of haemoglobin into plasma resulting in jaundice. So, now RBCs cannot provide oxygen for oxidation of food thereby causing deficiency of G-6-P dehydrogenase.

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