NEETBiologyChemical Coordination and IntegrationMCQ+4 / −1
Why can't insulin be given orally to diabetic patients?
- ABecause of structural variation
- BIts bioavailability will be increased
- CHuman body will elicit strong immune response
- DIt will be digested in Gastro-Intestinal (GI) tract
View written solutionFree
Correct answer: D
Insulin is a peptide hormone, so if taken by mouth:
It passes through the stomach’s acidic environment
Proteolytic enzymes in the GI tract break its peptide bonds
Practically none of the intact hormone reaches the bloodstream
Therefore the correct choice is Option D: It will be digested in the Gastro-Intestinal tract.
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