Which of the following factors are favourable for the formation of oxyhaemoglobin in alveoli?
- AHigh and High
- BHigh and Lesser concentration
- CLow and High concentration
- DLow and High temperature
View written solutionFree
Correct answer: B
The formation of oxyhemoglobin in the alveoli is primarily influenced by the partial pressure of oxygen ($\mathrm{pO}_2$), partial pressure of carbon dioxide ($\mathrm{pCO}_2$), hydrogen ion concentration ($\mathrm{H}^{+}$), and temperature. Understanding these factors will help in selecting the right option that describes the conditions favorable for maximizing the binding of oxygen to hemoglobin in the lungs.
1. Oxygen Partial Pressure ($\mathrm{pO}_2$): High $\mathrm{pO}_2$ enhances the formation of oxyhemoglobin. In the alveoli, where gas exchange occurs, the $\mathrm{pO}_2$ is relatively high, making it a favorable condition for oxyhemoglobin formation as oxygen molecules bind readily to hemoglobin.
2. Carbon Dioxide Partial Pressure ($\mathrm{pCO}_2$): Lower $\mathrm{pCO}_2$ is favorable in the alveoli for oxyhemoglobin formation. High $\mathrm{pCO}_2$ leads to a lower pH (due to formation of carbonic acid), which can cause the release of O2 from hemoglobin (Bohr effect), reducing hemoglobin's affinity for oxygen.
3. Hydrogen Ion Concentration ($\mathrm{H}^{+}$): Lesser $\mathrm{H}^{+}$ concentration, or higher pH, increases the affinity of hemoglobin for oxygen. In alkaline conditions (higher pH), hemoglobin is more likely to bind oxygen, thus forming oxyhemoglobin.
4. Temperature: Temperature also affects oxygen binding. Lower temperatures generally enhance the uptake of oxygen by hemoglobin. However, since the lung environment maintains a stable temperature, significant fluctuations in temperature are less of a consideration in this context compared to $\mathrm{pO}_2$, $\mathrm{pCO}_2$, and $\mathrm{H}^{+}$ concentration.
Given these points, Option B - High $\mathrm{pO}_2$ and Lesser $\mathrm{H}^{+}$ concentration - best describes the conditions that are favorable for the formation of oxyhemoglobin in the alveoli. High $\mathrm{pO}_2$ ensures that more oxygen molecules are available to bind with hemoglobin, and a lower $\mathrm{H}^{+}$ concentration (higher pH) reduces the release of oxygen from hemoglobin, thereby increasing oxygen uptake.
More from Breathing and Exchange of Gases
- Given below are two statements: One is labelled as Assertion A and the other is labelled as Reason R. Assertion A: During the transportation of gases, about 20-25 percent of CO is carried by Haemoglobin as carbamino-haemoglobin. Reason…2024 · MCQ
- Match List-I with List-II: Choose the correct answer from the options given below: Includes table2024 · MCQ
- Select the sequence of steps in Respiration. (A) Diffusion of gases (O2 and CO2) across alveolar membrane. (B) Diffusion of O2 and CO2 between blood and tissues. (C) Transport of gases by the blood (D) Pulmonary ventilation by which…2023 · MCQ
- Given below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R). Assertion (A) : A person goes to high altitude and experiences "Altitude Sickness" with symptoms like breathing difficulty and heart…2023 · MCQ
- Vital capacity of lung is ________.2023 · MCQ
- Identify the region of human brain which has pneumotaxic centre that alters respiratory rate by reducing the duration of inspiration.2022 · MCQ
- Which of the following statements are correct with respect to vital capacity? (a) It includes ERV, TV and IRV (b) Total volume of air a person can inspire after a normal expiration. (c) The maximum volume of air a person can breathe in…2022 · MCQ
- Under normal physiological conditions in human being every 100 ml of oxygenated blood can deliver ____________ ml of O2 to the tissues.2022 · MCQ